Acute Bacterial Skin and Skin Structure Infections (ABSSSI) are the type of skin that affects the epidermis, dermis, and subcutaneous tissues. The US FDA defines ABSSSI as lesions with cellulitis / erysipelas, wound infections, and major cutaneous abscesses occurring in a minimum surface area of 75 cm 2. Pathogens such as Methicillin sensitive Staphylococcus aureus (MSSA), Methicillin resistant Staphylococcus aureus (MRSA), Beta-hemolytic Streptococcus, Escherichia coli, Enterococcus faecalis, and Pseudomonas aeruginosa are the major causes of ABSSSI.
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Prevalence of drug resistant strains, especially in Staphylococcus spp. and Enterococcus spp. Approved in the forecast period.
The major market driver for the growth of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) is increasingly developing and developing pharmaceutical and biopharmaceutical products. For instance, in 2017, Cempra announced promising data from the phase 3 trial of Fusidic acid for the treatment of ABSSSI. In the same year, Melinta Therapeutics received US FDA for its product Baxdela, a delafloxacin based ABSSSI medicine, available in both intravenous and oral formulations. Moreover, in 2018, Fresenius Kabi received FDA approval for new drug application of daptomycin, a lipopeptide class of antibacterial drug, in injectable form for complicated skin and skin structure infections (cSSSI) caused by susceptible Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes,
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Key vendors:
Paratek Pharmaceuticals, Inc., Melinta Therapeutics, Inc., Allergan PLC, Merck & Co., Inc., Accord Healthcare Ltd. (a subsidiary of Intas Pharmaceuticals Ltd.), Fresenius SE & Co. KGaA, Sandoz Inc. (a subsidiary of Novartis), Glenmark Pharmaceuticals Ltd, Cadila Healthcare Ltd., and Teva Pharmaceutical Industries Ltd.
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