Retroperitoneal liposarcoma (RLS) is a rare, biologically heterogeneous cancer, which occurs in retroperitoneum, lining the abdominal organs. Retroperitoneal liposarcoma grows continuously and may not be diagnosed until they are very large, so its prognosis is poor compared to the other subtypes of retroperitoneal sarcomas. The reason for the development of these tumors is still unknown, however, genetic mutation is considered as one of the factors leading to the generation of tumors. Incidence of this disease is equal in men and women, with a slight predominance of men. This tumor has no symptoms and is usually diagnosed during the advanced stage.
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Furthermore, the effectiveness of radiotherapy or chemotherapy for the treatment of cancer is not well defined. However, affected population who received adjuvant chemotherapy showed survival benefits and improvement, as compared to patients who underwent surgery alone. In the case of surgeries, sometimes, preoperative radiation is given to shrink the tumor. This will make the surgery technically more feasible.
The European Organization for Research and Treatment of Cancer (EORTC) is currently conducting a randomized trial comparing 50.4Gy (gray-to-measure radiation therapy) of pre-operative radiation therapy with short-course radiotherapy. During the prognosis period, the treatment of the leucorrhoea in the retroperitoneal liposarcoma treatment market will take place.
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Key vendors:
Eli Lilly and Company, Baxter International, Bristol Laboratories Ltd., Pfizer Inc., Teva Pharmaceutical Industries Ltd., Mylan NV, Actavis plc, Fresenius Kabi Ltd., Accord Healthcare Inc., Taro Pharmaceuticals Inc., Sandoz, Bedford Laboratories, and Zydus Cadila.
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